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 Industry : |
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Pharmaceutical |
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| Product : |
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2% Budesonide dispersion in water |
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| Test Objective : |
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Reduce the particle size of Budesonide so that 90% of particles are below 1 um |
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| Processor : |
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M-110Y vs M-140K (Microfluidizer High Shear Processor 장비보기) |
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| Chambers : |
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Interaction Chamber (downstream) G10Z (87 um)
Auxiliary Processing Module (upstream) H30Z (200 um) |
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| Number of passes : |
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40 passes (M-110Y), 32 passes (M-140K) |
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| Shear per pass : |
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Approx. 5,900,000 sec -1 (M-110Y) @ 23,000 psi
Approx. 7,800,000 sec -1 (M-140K) @ 23,000 psi |
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| Process pressure : |
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23,000 psi (M-110Y), 40,000 psi (M-140K) |
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| Summary of results : |
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The M-140K Microfluidizer processor reduced 90% of particles to 0.649 um in 32 passes vs the M-110Y,
which reduced 57.4 % of particles to 0.960 um in 40 passes
(pdf 화일 다운로드) |
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