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Industry : Pharmaceutical
Product : 2% Budesonide dispersion in water
Test Objective : Reduce the particle size of Budesonide so that 90% of particles are below 1 um
Processor : M-110Y vs M-140K     (Microfluidizer High Shear Processor Àåºñº¸±â)
Chambers : Interaction Chamber (downstream) G10Z (87 um)
Auxiliary Processing Module (upstream) H30Z (200 um)
Number of passes : 40 passes (M-110Y), 32 passes (M-140K)
Shear per pass : Approx. 5,900,000 sec -1 (M-110Y) @ 23,000 psi
Approx. 7,800,000 sec -1 (M-140K) @ 23,000 psi
Process pressure : 23,000 psi (M-110Y),   40,000 psi (M-140K)
Summary of results : The M-140K Microfluidizer processor reduced 90% of particles to 0.649 um in 32 passes vs the M-110Y, which reduced 57.4 % of particles to 0.960 um in 40 passes
(pdf È­ÀÏ ´Ù¿î·Îµå)











 
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