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¿µÁøÄÚÆÛ·¹ÀÌ¼Ç Á¾ÇÕÄ«´Ù·Î±×
Superior Growth and Expansion of hMSCs Derived from a Variety of Sources, including Bone Marrow (BM-MSC), Adipose Tissue (AT-MSC) and Umbilical Cord Matrix (UC-MSC)
 
- MSC NutriStem Culture System Datasheet (product datasheet)
- MSC NutriStem XF Medium Scientific References (scientific reference)
- Passaging MSC Using NutriStem¢ç XF Medium and Human Platelet Lysate (application note)
- MSC NutriStem¢ç XF Medium (application note)
- Assuring Multipotency of Human Mesenchymal Stem Cells (white paper)
- MSC NutriStem¢ç XF Medium Manual (manual)


 
 
¡î hMSCs (Human Mesenchymal Stem Cell) Áٱ⼼Æ÷ÀÇ ¹è¾çÀº ¹è¾çȯ°æ, ¹è¾ç¾×ÀÇ ¼ººÐ µî¿¡ Å« ¿µÇâÀ» ¹Þ½À´Ï´Ù. Sartorius »çÀÇ MSC NutriStem¢ç XF Medium Àº hMSC ¼¼Æ÷ÀÇ isolation, expansion, ±×¸®°í differentiation À» ¿Ïº®ÇÏ°Ô Áö¿øÇÕ´Ï´Ù.
¡î Completely Defined, Xeno-free and Serum-free ¹è¾ç¾× ÀÔ´Ï´Ù.
¡î hMSC ¼¼Æ÷ÀÇ morphology ¿Í karyotype À» Á¤»óÀûÀÌ°í ¾ÈÁ¤ÀûÀ¸·Î À¯Áö Çϸ鼭 Àå±â°£¿¡ °ÉÃÄ ¹è¾çÀ» ÇÒ ¼ö ÀÖ½À´Ï´Ù.
¡î hMSC ¼¼Æ÷¸¦ Àå±â ¹è¾çÇϸ鼭µµ tri-lineage differentiation potential À» À¯ÁöÇÒ ¼ö ÀÖ°Ô ÇÕ´Ï´Ù.
¡î hMSC ¼¼Æ÷ÀÇ Áõ½Ä (proliferation) ½ÃÅ°´Â ´É·ÂÀÌ Å¹¿ùÇÑ medium ÀÔ´Ï´Ù.
¡î ¿øÀç·á, ¾ÈÀü¼º µ¥ÀÌÅÍ, È¿´É µ¥ÀÌÅÍ µî°ú °ü·ÃµÈ Á¤º¸ÀÎ Drug Master File (DMF) Á¦°øÀÌ °¡´ÉÇÕ´Ï´Ù.
¡î ISO 13408 °ú cGMP guideline ¿¡ ÀûÇÕÇÏ°Ô Á¦Á¶µÈ media
¡î ´ÙÀ½ ½Ã¾àµéÀº MSC NutriStem¢ç XF Medium °ú °°ÀÌ »ç¿ëµÉ ¼ö ÀÖµµ·Ï ÃÖÀûÈ­ µÇ¾îÀÖ½À´Ï´Ù.
- Platelet Lysate,   Attachment Solutions,   Cell Dissociation Reagents,   Differentiation Media


PLTGold¢ç Human Platelet Lysate
¡î xeno-free, animal serum-free human platelets ÃßÃâ¹° ÀÔ´Ï´Ù.
¡î hMSC ¼¼Æ÷ÀÇ ¼ºÀå¿¡ ÇÊ¿äÇÑ ¸ðµç growth factors ¿Í proteins µéÀÌ µé¾îÀÖ½À´Ï´Ù.
¡î cGMP ±Ô°Ý ÀûÇÕ ¼³ºñ¿¡¼­ Á¦Á¶ µÇ¾úÀ¸¸ç Drug Master File (DMF) Á¦°øÀÌ °¡´ÉÇÕ´Ï´Ù.

MSC Attachment Solution
¡î hMSC ¼¼Æ÷¸¦ serum-free Á¶°Ç¿¡¼­ ¹è¾çÇÒ ¶§¿¡´Â ¼¼Æ÷¸¦ adherence ½ÃÅ°´Â factor °¡ ÇÊ¿äÇÕ´Ï´Ù.
¡î hMSC ¼¼Æ÷ÀÇ attachment, cell spreading, growth, morphology, differentiation, and motility ¸¦ ÃËÁø ½ÃÅ°´Â ±â´ÉÀ» ÇÕ´Ï´Ù.

Reliable Recombinant Trypsin for hMSC Dissociation
¡î Recombinant Trypsin Solutions Àº contamination ¿°·Á°¡ ¾ø´Â cell dissociating reagent ÀÓ.
¡î hMSC ¼¼Æ÷¿Í °°ÀÌ ¸Å¿ì sensitive ÇÑ ¼¼Æ÷ÀÇ dissociation ¿¡ ÀûÇÕÇÕ´Ï´Ù.

MSCgo¢â Differentiation Media
¡î Human Mesenchymal Stem Cells À» adipocytes, chondrocytes, ±×¸®°í osteoblasts ·ÎÀÇ ºÐÈ­¸¦ ½Å·Ú¼º°ú ÀçÇö¼º ÀÖ°Ô ÁøÇà½ÃÄÑ ÁÖ´Â reagent ÀÔ´Ï´Ù.
¡î hMSC-AT, hMSC-BM, ±×¸®°í hMSC-CT °°Àº ´Ù¾çÇÑ ±â¿øÀÇ hMSC ¼¼Æ÷ÀÇ ºÐÈ­¿¡ È¿À²ÀûÀ¸·Î »ç¿ë
¡î Serum-free and xeno-free
¡î hMSC ¼¼Æ÷ÀÇ ¼ºÀå°ú ºÐÈ­¿¡ ÇÊ¿äÇÑ ¸ðµç growth factors ¿Í supplements ¸¦ °¡Áö°í ÀÖ½À´Ï´Ù.



Peformance Test


¡á Superior Proliferation and Expansion of hMSCs
Note :: MSC NutriStem¢ç XF Medium promotes superior proliferation and expansion of BM-hMSCs compared to other serum-free and serum-containing media


¡á Long-Term Growth of hMSCs
Note :: MSC NutriStem¢ç XF Medium promotes superior long-term growth of AT-hMSCs compared to other serum-free and serum-containing media


¡á High Expression of Mesenchymal Stem Cell Markers
Note :: Immunophenotyping results of AT-hMSCs at passage 2 using FACS analysis. hMSCs cultured in MSC NutriStem¢ç XF Medium were found to be >99% positive for CD73, CD90 and CD105.


¡á Differentiation Potential : Adipocytes, Osteocytes and Chondrocytes
Note :: Humna AT-hMSCs were expanded in MSC NutriStem¢ç XF Medium for 3-5 passages before differentiation. Representative images show stained adipocytes, osteocytes and chondrocytes.



Ordering Information
Product Name Order Number Size
MSC NutriStem¢ç XF Medium with Phenol Red 500 ml 05-200-1A
MSC NutriStem¢ç XF Basal Medium without Phenol Red 500 ml 05-202-1A
MSC NutriStem¢ç XF Supplement Mix 3 ml 05-201-1U
Recombinant Trypsin Solution 100 ml 03-078-1B
Recombinant Trypsin EDTA Solution 500 ml 03-079-1A
NutriCoat¢â Attachment Solution 1.5 ml 05-760-1-15
NutriFreez¢ç D5 Cryopreservation Solution 500 ml 05-715-1A
PLTGold¢ç Human Platelet Lysate (Research Grade) 100 ml PLTGOLD100R
PLTGold¢ç Human Platelet Lysate (Clinical Grade) 100 ml PLTGOLD100GMP



 
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